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Kinase-Targeted Therapeutics Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2016 - 2024

Report Description

Kinase-Targeted Therapeutics Market: Overview

Kinase is an enzyme class that helps to transfer phosphate groups to certain substrate from high energy molecules such as adenosine triphosphate (ADP). This phenomenon of phosphate group transfer is termed as phosphorylation. Kinases control various cellular activities such as cell signaling, cellular transport, protein regulation, secretory processes and cellular metabolism. Based on the molecule on which kinases act, they can be categorized as: protein kinase, lipid kinase, carbohydrate kinase and other kinase (thymidine kinase and riboflavin kinase). Protein kinases include mitogen activated protein kinases and cyclin dependent kinases. Lipid kinases include sphingosine kinases and phosphatidylinositol kinases.

Protein kinase acts on tyrosine, serine, histidine or threonine content of protein and modify the protein functionality by either increasing or decreasing their activities. Lipid kinase acts on the cell or plasma membrane along with organelles membrane. Activity of kinase on membrane helps alter reactivity of lipids and hence result in signal transmission. Carbohydrate kinases (hexokinase and phosphofructokinase) act on bisphosphoglycerate and other carbohydrate molecule to release energy. Among all the aforementioned kinases, protein kinases therapeutics accounts for the largest share of the total market owing to their wider application area coupled with their large utilization in developing and manufacturing therapeutic drugs.

Many diseases are caused due to inappropriate activities of kinases. Aberrant kinase activities also results in proliferative or inflammatory responses for the diseases such as cancer and rheumatoid arthritis. Kinase activities have also resulted in cardiovascular diseases, diabetes and neurological disorders. Hence, any disruption in the activities of any of the kinase may result in adverse effects on the people. Kinase-targeted therapeutics include all those drugs that act on the kinases that are affecting negatively to the people. These drugs enable the physicians to treat the disease from the root cause and help eliminating the adverse effects of the disease.

Kinase-Targeted Therapeutics Market: Driving Forces

Owing to rising incidences of diabetes the population, the market for kinase-targeted therapeutics is poised to grow at a significant CAGR from the period 2013 to 2019. The World Diabetes Foundation (WDF) has estimated that nearly 285 million populace lived with diabetes in the year 2010 that accounted for 6.4% of the world’s youth population in the same year. This number is poised to grow to 438 million by 2030, corresponding to 7.8% of the world’s adult population. The National Diabetic Fact Sheet of the U.S., which was released in January 2011, states that 25.8 million children and adults suffer from diabetes which accounts for 8.3% of the total U.S. population.

Almost 1.9 million new cases were diagnosed in people aged 20 years and above in the U.S. alone. Similarly, increasing number of cancer patients across the globe also augments the growth of kinase-targeted therapeutics market. It has been estimated by the World Cancer Research Fund International that by 2030 around 21 million people will suffer from cancer worldwide.

Kinase-Targeted Therapeutics Market: Regional Dynamics

In 2012, North America accounted for the largest share of global kinase-targeted therapeutics market owing to presence of large geriatric population. Elder people are prone to various diseases such as cardiovascular diseases and other that can be easily treated by the uptake of kinase-targeted therapeutic drugs.

Similarly, domicile of big manufacturers of kinase-targeted therapeutic drugs in the region has further supported the large market size of kinase-targeted therapeutics market. The major players operating in kinase-targeted therapeutics market include Abbott Laboratories, Eli Lilly and Company, Array BioPharma, Inc., Avila Therapeutics, Inc. and Bristol-Myers Squibb Co amongst other significant players.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, Luxembourg)
  • Eastern Europe (Poland, Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market

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