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Synthetic Antispasmodics and Anticholinergics Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2016 - 2023

Report Description

Synthetic Antispasmodics and Anticholinergics Market

Synthetic drugs are produced in a laboratory employing various chemical reactions. The chemical structure of these synthetic drugs match naturally occurring drugs and they are designed in such as way as to enhance their effects as compared to naturally occurring drugs, or to prevent undesired side effects. Many synthetic compounds without an alternative natural source are classified by the chemical structure of the parent synthetic compound. Pharmacological activity within a group of common sore structure may vary widely and produce different effects. The mechanism of action of anticholinergic drugs involves blocking of acetylcholine, nicotine, or muscarinic receptors. Distribution of the muscarinic receptors is known to be in the central nervous system (CNS), cardiac muscle, smooth muscle, and the salivary glands. Nicotinic receptors are present in the autonomic ganglia and on striated muscle. Antispasmodic agents inhibit similar mechanism of action to anticholinergics. They act by blocking the parasympathetic nerve impulses leading to reduced smooth muscle spasms in the bladder and the gastrointestinal tract.

Synthetic Antispasmodics and Anticholinergics Market: Segmentation

The anticholinergics and antispasmodics in clinical use include natural, semi-synthetic and synthetic compounds that demonstrate a multitude of actions on smooth muscle cells and the parasympathetic nervous system.  They are used to treat spasms or conditions with disturbances in the bladder or gastrointestinal motility. They are administered to treat functional gastrointestinal disorders. The global synthetic antispasmodic and anticholinergic drugs market has been segmented based on the drug class. This includes synthetic anticholinergics, as esters with tertiary amino group (oxyphencyclimine, camylofin, mebeverine, trimebutine, rociverine, dicycloverine, others), synthetic anticholinergics, as quaternary ammonium compounds (benzilone, glycopyrronium, oxyphenonium, penthienate, propantheline, carbachol, bevonium, poldine, diphemanil, mepenzolate and others), synthetic antispasmodic, as amides with tertiary amines (dimethylaminopropionylphenothiazine, nicofetamide, tiropramide), synthetic anticholinegic agents in combination with psycholeptics (isopropamide with psycholeptics, clidinium with psycholeptics and others), synthetic antispasmodic agents in combination with analgesics (tropenzilone with analgesics, bevonium with analgesics and others), combination of antispasmodics, psycholeptics and analgesics and synthetic antispasmodic agents with others drugs.

Synthetic Antispasmodics and Anticholinergics Market: Drivers and Restraints

The bulky ammonium side chain in the synthetic quaternary ammonium derivatives makes these derivatives less likely to cross membranes, such as  the blood brain barrier, and thus less likely to have central nervous system effects.  Commercial production of synthetic drugs is carried out by drug manufacturers for valid medical purposes, however may lead to diversion from legal channels across the globe worldwide. Laboratory control knowledge, chemistry background and an educated understanding of the process is generally required for successful and safe synthesis of the drugs.

Antimuscarinic antispasmodic agents can be divided into atropine and related belladonna alkaloids, and the synthetic antimuscarinics (tertiary amine and quaternary ammonium compounds). In gastroenterology these agents are used in the relief of muscle spasm: anticholinergics have a dramatic effect on smooth muscle spasm when administered IV, but orally the effect is often disappointing; and for suppression of gastric acid secretion, where the high doses needed are often associated with considerable side-effects. More selective gastric acid antisecretory agents are preferable and have largely superseded agents formerly used. In the treatment of irritable bowel syndrome, often a therapeutic dilemma, there is some evidence that a high fibre maintenance diet combined with short- term antispasmodics may be beneficial.

Some of the players contributing to the global synthetic antispasmodics and anticholinergics market include Shire U.S, Khandelwal Laboratories Pvt Ltd., Hospira, Inc., Dr. Reddys Laboratories Ltd., Watson Laboratories, Inc., Ranbaxy, Inc. and CorePharma, Inc.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, Luxembourg)
  • Eastern Europe (Poland, Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market

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